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Non-peptide dysbiosis metabolites reprogram a peptide quorum-sensing receptor to induce sustained predation in beneficial streptococci

Non-peptide dysbiosis metabolites reprogram a peptide quorum-sensing receptor to induce sustained predation in beneficial streptococci

Microbial dysbiosis alters chemical cues in the oral microbiome, but how commensals sense these changes is unclear. This study shows that Streptococcus salivarius detects dysbiosis metabolites and repurposes a peptide quorum-sensing receptor to drive sustaine…

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